KCNH1

Across TCGA patient cohorts, KCNH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,478 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KCNH1-associated proteins across cancer lineages are AGO1, PXN_S322, and TRIM2. Each is linked with KCNH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNH1-to-partner and partner-to-KCNH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH1 versus AGO1 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH1→partner) and Y-score (partner→KCNH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AGO1 →	+0.279	+0.286	<.001	<.001	3	5
LSCC	PXN_S322 →	-0.578	-0.505	<.001	<.001	3	5
HNSC	TRIM2 →	+0.665	+0.505	<.001	<.001	3	5
GBM	RRBP1_T275 →	-0.771	-0.971	<.001	<.001	3	4
BRCA	SMC2 →	-0.399	-0.432	.001	.002	3	4
GBM	SPTAN1 →	+0.334	+0.692	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,478 associations by consensus.

KCNH1 vs AGO1 — UCEC

Explore this scatter interactively →