KCNG3

Across TCGA patient cohorts, KCNG3 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNG3-associated genes across cancer lineages are Ku80, PCNA, and Src. Each is linked with KCNG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNG3-to-partner and partner-to-KCNG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by KCNG3-low versus KCNG3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG3→partner) and Y-score (partner→KCNG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.382	+3.183	.003	.010	3	1
UCEC	PCNA →	+0.239	+3.169	.043	.020	3	1
UCEC	Src →	-0.319	-3.169	.004	.020	3	1
UCEC	cIAP →	+0.177	+2.817	.019	.036	3	1
UCEC	Cyclin-E2 →	+0.196	+2.817	.033	.036	3	1
UCEC	eIF4E →	+0.322	+3.169	.005	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Ku80 by KCNG3 expression — UCEC

Explore this box plot interactively →