KCNG3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNG3 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KCNG3-associated genes across cancer lineages are MRGPRG, CCL7, and KLHL40. Each is linked with KCNG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNG3-to-partner and partner-to-KCNG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRGPRG grouped by KCNG3-low versus KCNG3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG3→partner) and Y-score (partner→KCNG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaMRGPRG →+0.056+5.209<.001.00532
BLOOD_LymphomaCCL7 →+0.098+4.867<.001.00931
BLOOD_LymphomaKLHL40 →+0.013+5.209<.001.00531
BLOOD_LymphomaSMCP →+0.040+4.867<.001.00931
BLOOD_LymphomaCST9 →+0.119+5.209<.001.00531
BLOOD_LymphomaFABP12 →+0.095+5.643<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

MRGPRG by KCNG3 expression — BLOOD_Lymphoma

Box plot of MRGPRG in KCNG3-low vs KCNG3-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration