KCNG2

Across TCGA patient cohorts, KCNG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,107 significant associations in total. OV shows the largest number of these associations.

The most reproducible KCNG2-associated GO terms across cancer lineages are Notch signaling pathway, Negative regulation of striated muscle cell differentiation, and Regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Each is linked with KCNG2 in more than 20 cancer types. Because this analysis shows association rather than direction, both KCNG2-to-partner and partner-to-KCNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch signaling pathway grouped by KCNG2-low versus KCNG2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG2→partner) and Y-score (partner→KCNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Notch signaling pathway →	+0.040	+0.260	<.001	<.001	3	21
ESCA	Negative regulation of striated muscle cell differentiation →	+0.051	+0.386	<.001	<.001	3	20
ESCA	Regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.050	+0.292	<.001	<.001	3	20
ESCA	Regulation of peptidyl-tyrosine phosphorylation →	+0.043	+0.330	<.001	<.001	3	20
ESCA	Peptidyl-tyrosine modification →	+0.041	+0.309	<.001	<.001	3	20
ESCA	Regulation of endocytosis →	+0.036	+0.292	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,107 associations by consensus.

Notch signaling pathway by KCNG2 expression — ESCA

Explore this box plot interactively →