KCNG2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNG2 mutation is significantly associated with the RNA expression of many other genes, with 934 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KCNG2-associated genes across cancer lineages are MIR548D2, ATP5F1A, and RN7SL664P. Each is linked with KCNG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNG2-to-partner and partner-to-KCNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR548D2 grouped by KCNG2-low versus KCNG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG2→partner) and Y-score (partner→KCNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR548D2 →+0.221+2.957.008.00933
COADATP5F1A →+0.639+3.362<.001.00533
SKCMRN7SL664P →+0.135+2.894<.001.00333
COADSLX4 →+0.415+3.335.006.00532
COADRPL17-C18orf32 →+0.079+2.840<.001.00132
COADZNF232-AS1 →+0.522+3.200.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

MIR548D2 by KCNG2 expression — UCEC

Box plot of MIR548D2 in KCNG2-low vs KCNG2-high samples in UCEC.

Explore this box plot interactively →

Exploration