KCNG2

Across TCGA cell cohorts, KCNG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,603 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNG2-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with KCNG2 in more than 11 cancer types. Because this analysis shows association rather than direction, both KCNG2-to-partner and partner-to-KCNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by KCNG2-low versus KCNG2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG2→partner) and Y-score (partner→KCNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.145	+0.171	<.001	.008	3	12
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.145	+0.171	<.001	.008	3	12
SOFT_TISSUE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.148	+0.220	<.001	<.001	3	10
SKIN	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.109	+0.114	<.001	<.001	3	9
STOMACH	mRNA transport →	+0.092	+0.159	.001	.007	3	9
SOFT_TISSUE	RNA export from nucleus →	+0.096	+0.237	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

Negative regulation of DNA-templated transcription initiation by KCNG2 expression — STOMACH

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