KCNG2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNG2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNG2-associated genes across cancer lineages are C1orf87, OR1M1, and OR9A2. Each is linked with KCNG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNG2-to-partner and partner-to-KCNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by KCNG2-low versus KCNG2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG2→partner) and Y-score (partner→KCNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaC1orf87 →+0.056+4.867<.001.00931
BLOOD_LymphomaOR1M1 →+0.019+5.209<.001.00531
BLOOD_LymphomaOR9A2 →+0.018+5.209<.001.00531
BLOOD_LeukemiaHSD3B1 →+0.052+3.455.003.00231
LARGE_INTESTINESERAC1 →+0.666+3.067.004.00931
LARGE_INTESTINEVAX1 →+0.682+2.782<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

C1orf87 by KCNG2 expression — BLOOD_Lymphoma

Box plot of C1orf87 in KCNG2-low vs KCNG2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration