KCNG1

Across TCGA cell cohorts, KCNG1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KCNG1-associated genes across cancer lineages are OR2L8, OR13C2, and OR5V1. Each is linked with KCNG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNG1-to-partner and partner-to-KCNG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L8 grouped by KCNG1-low versus KCNG1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG1→partner) and Y-score (partner→KCNG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2L8 →	+0.026	+3.280	<.001	.002	3	3
LUNG_SCLC	OR13C2 →	+0.075	+3.898	<.001	.005	3	2
SKIN	OR5V1 →	+0.016	+4.977	<.001	.007	3	2
OVARY	OR10G4 →	+0.015	+3.339	<.001	.004	3	2
OVARY	OR11A1 →	+0.004	+3.781	<.001	.001	3	2
PANCREAS	CRYBB1 →	+0.019	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

OR2L8 by KCNG1 expression — OVARY

Explore this box plot interactively →