KCNF1

Across TCGA cell cohorts, KCNF1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNF1-associated genes across cancer lineages are ASZ1, CALHM4, and PROP1. Each is linked with KCNF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNF1-to-partner and partner-to-KCNF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by KCNF1-low versus KCNF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNF1→partner) and Y-score (partner→KCNF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASZ1 →	+0.119	+4.152	.001	.009	3	1
BLOOD_Leukemia	CALHM4 →	+0.038	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	PROP1 →	+0.032	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1
LARGE_INTESTINE	CD207 →	+0.170	+3.374	<.001	.005	3	1
LARGE_INTESTINE	CILP →	+0.140	+3.706	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ASZ1 by KCNF1 expression — BLOOD_Leukemia

Explore this box plot interactively →