KCNE5

Across TCGA patient cohorts, KCNE5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,145 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible KCNE5-associated GO terms across cancer lineages are Regulation of actin filament organization, Collagen metabolic process, and Positive regulation of epithelial to mesenchymal transition. Each is linked with KCNE5 in more than 18 cancer types. Because this analysis shows association rather than direction, both KCNE5-to-partner and partner-to-KCNE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by KCNE5-low versus KCNE5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE5→partner) and Y-score (partner→KCNE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of actin filament organization →	+0.033	+0.148	<.001	<.001	3	19
ESCA	Collagen metabolic process →	+0.065	+0.331	<.001	<.001	3	19
ESCA	Positive regulation of epithelial to mesenchymal transition →	+0.056	+0.224	.002	.001	3	18
PAAD	Platelet-derived growth factor receptor-beta signaling pathway →	+0.081	+0.385	<.001	<.001	3	18
ESCA	Extracellular matrix assembly →	+0.064	+0.366	<.001	<.001	3	18
STAD	Stress fiber assembly →	+0.037	+0.152	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,145 associations by consensus.

Regulation of actin filament organization by KCNE5 expression — STAD

Explore this box plot interactively →