KCNE4

Across TCGA patient cohorts, KCNE4 mutation is significantly associated with the RNA expression of many other genes, with 3,121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNE4-associated genes across cancer lineages are RN7SKP245, SPANXN4, and MIR656. Each is linked with KCNE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNE4-to-partner and partner-to-KCNE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP245 grouped by KCNE4-low versus KCNE4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE4→partner) and Y-score (partner→KCNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP245 →	+0.127	+5.812	<.001	.003	3	2
LIHC	SPANXN4 →	+0.306	+6.479	<.001	.001	3	2
LIHC	MIR656 →	+0.641	+5.186	<.001	.007	3	2
LIHC	RNU2-59P →	+0.382	+5.186	<.001	.007	3	2
LIHC	MTND1P4 →	+0.142	+5.355	<.001	.005	3	2
UCEC	YBX1P9 →	+0.098	+2.008	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,121 associations by consensus.

RN7SKP245 by KCNE4 expression — CESC

Explore this box plot interactively →