KCNE4

Across TCGA cell cohorts, KCNE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,912 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCNE4-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Schwann cell differentiation, and Vesicle cargo loading. Each is linked with KCNE4 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCNE4-to-partner and partner-to-KCNE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by KCNE4-low versus KCNE4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE4→partner) and Y-score (partner→KCNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.076	+1.802	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Schwann cell differentiation →	+0.114	+0.147	<.001	.006	3	8
LIVER	Vesicle cargo loading →	+0.108	+3.038	.004	.001	3	7
SKIN	Vacuole organization →	+0.037	+1.439	.001	.003	3	7
SKIN	Regulation of transforming growth factor beta receptor signaling pathway →	+0.048	+1.504	<.001	.001	3	7
SKIN	Regulation of cellular response to transforming growth factor beta stimulus →	+0.054	+1.859	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,912 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by KCNE4 expression — SKIN

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