KCNE1B

Across TCGA patient cohorts, KCNE1B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,864 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KCNE1B-associated GO terms across cancer lineages are Osteoclast differentiation, Positive regulation of macrophage migration, and Activation of innate immune response. Each is linked with KCNE1B in more than 13 cancer types. Because this analysis shows association rather than direction, both KCNE1B-to-partner and partner-to-KCNE1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoclast differentiation grouped by KCNE1B-low versus KCNE1B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE1B→partner) and Y-score (partner→KCNE1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Osteoclast differentiation →	+0.048	+0.051	<.001	<.001	3	14
GBM	Positive regulation of macrophage migration →	+0.060	+0.093	<.001	<.001	3	13
LAML	Activation of innate immune response →	+0.044	+0.430	<.001	<.001	3	13
STAD	Myeloid leukocyte differentiation →	+0.049	+0.045	<.001	<.001	3	13
LAML	Macrophage activation →	+0.064	+0.418	<.001	<.001	3	13
LAML	Myeloid leukocyte cytokine production →	+0.054	+0.364	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,864 associations by consensus.

Osteoclast differentiation by KCNE1B expression — STAD

Explore this box plot interactively →