KCNE1

Across TCGA cell cohorts, KCNE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,765 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNE1-associated GO terms across cancer lineages are Medulla oblongata development, Pons development, and Protein targeting to lysosome involved in chaperone-mediated autophagy. Each is linked with KCNE1 in more than 9 cancer types. Because this analysis shows association rather than direction, both KCNE1-to-partner and partner-to-KCNE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Medulla oblongata development grouped by KCNE1-low versus KCNE1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE1→partner) and Y-score (partner→KCNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Medulla oblongata development →	-0.249	-1.084	<.001	<.001	3	10
SOFT_TISSUE	Pons development →	-0.092	-0.522	<.001	.004	3	7
LIVER	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.130	+0.241	.004	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.079	+0.094	<.001	.001	3	6
LIVER	Protein folding →	+0.078	+0.296	<.001	.006	3	6
BONE	Negative regulation of calcineurin-mediated signaling →	+0.312	+0.403	<.001	.008	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,765 associations by consensus.

Medulla oblongata development by KCNE1 expression — BLOOD_Leukemia

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