KCND3-AS1

Across TCGA pan-cancer cohorts, KCND3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated KCND3-AS1 data layer.

The strongest signal is observed in thymoma (THYM), where higher KCND3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCND3-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRC show a favorable association.

THYM, THCA, and BLCA are the cancer types where KCND3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.279	0.900	<.001	57	view →
THCA	OS	Tertile	III,IV	0.761	0.952	.001	48	view →
BLCA	OS	Tertile	IV	0.059	0.592	<.001	33	view →
ESCA	DFS	Tertile	III,IV	0.565	0.266	.001	24	view →
KIRC	DFS	Tertile	II,III,IV	0.690	0.506	.020	24	view →
HNSC	DFS	Tertile	All	0.461	0.282	.022	21	view →
COAD	OS	Tertile	All	1.000	0.784	.005	21	view →
ACC	DFS	Tertile	All	0.119	0.600	.006	18	view →
LAML	DFS	Tertile	All	0.167	0.587	.031	18	view →
UCS	DFS	Tertile	II,III,IV	0.826	0.366	.026	18	view →
BRCA	OS	Tertile	III,IV	0.904	0.796	.026	16	view →
LUAD	OS	Tertile	All	0.830	0.323	.020	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

KCND3-AS1–THYM (OS)

Open the THYM breakdown →