Across TCGA patient cohorts, KCND2 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCND2-associated genes across cancer lineages are FOXO3a, Ku80, and Cyclin-B1. Each is linked with KCND2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCND2-to-partner and partner-to-KCND2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCND2→partner) and Y-score (partner→KCND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	FOXO3a →	+0.225	+3.000	.024	.034	3	4
LUSC	Ku80 →	+0.318	+3.321	.022	.009	3	3
UCEC	Cyclin-B1 →	+0.434	+1.736	.004	.005	3	3
COAD	ASNS →	+0.548	+2.008	<.001	.018	3	3
STAD	Cyclin-E2 →	+0.187	+1.895	<.001	.025	3	2
LUSC	PDK1 →	-0.117	-2.691	.020	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

KCND2 survival (RNA) · tumor vs normal (RNA) · all KCND2 data types