KCND1

Across TCGA patient cohorts, KCND1 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCND1-associated genes across cancer lineages are TFRC, C-Raf, and ERK2. Each is linked with KCND1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCND1-to-partner and partner-to-KCND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by KCND1-low versus KCND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCND1→partner) and Y-score (partner→KCND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.379	+1.263	.019	.019	3	3
UCEC	C-Raf →	+0.131	+1.736	.002	.006	3	3
UCEC	ERK2 →	+0.123	+1.415	.037	.040	3	2
SKCM	p62 Lck ligand →	+0.414	+2.459	.025	.020	3	2
UCEC	PDCD4 →	-0.469	-1.473	.001	.006	3	2
UCEC	Rad50 →	-0.167	-1.064	.024	.048	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

TFRC by KCND1 expression — UCEC

Explore this box plot interactively →