KCND1

Across TCGA cell cohorts, KCND1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCND1-associated genes across cancer lineages are C18orf63, ADIG, and LCE2A. Each is linked with KCND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCND1-to-partner and partner-to-KCND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by KCND1-low versus KCND1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCND1→partner) and Y-score (partner→KCND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C18orf63 →	+0.039	+4.705	<.001	.003	3	2
BLOOD_Leukemia	ADIG →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	LCE2A →	+0.053	+4.969	<.001	.003	3	1
BLOOD_Leukemia	GUCA2A →	+0.039	+4.969	<.001	.003	3	1
BLOOD_Leukemia	CCT8L2 →	+0.014	+4.874	<.001	.002	3	1
BLOOD_Leukemia	KRTAP7-1 →	+0.071	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C18orf63 by KCND1 expression — BLOOD_Leukemia

Explore this box plot interactively →