KCNC4

Across TCGA cell cohorts, KCNC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,435 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNC4-associated GO terms across cancer lineages are Regulation of translational initiation, Nucleoside triphosphate metabolic process, and Purine ribonucleoside triphosphate metabolic process. Each is linked with KCNC4 in more than 11 cancer types. Because this analysis shows association rather than direction, both KCNC4-to-partner and partner-to-KCNC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by KCNC4-low versus KCNC4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC4→partner) and Y-score (partner→KCNC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.082	+0.789	.001	<.001	3	12
OESOPHAGUS	Nucleoside triphosphate metabolic process →	+0.113	+0.890	<.001	.001	3	11
OESOPHAGUS	Purine ribonucleoside triphosphate metabolic process →	+0.089	+0.690	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Canonical glycolysis →	+0.090	+0.667	.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Glucose catabolic process to pyruvate →	+0.090	+0.667	.001	.003	3	11
OESOPHAGUS	ATP metabolic process →	+0.130	+1.377	.002	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,435 associations by consensus.

Regulation of translational initiation by KCNC4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →