KCNC2

Across TCGA cell cohorts, KCNC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 97 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KCNC2-associated GO terms across cancer lineages are Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, Positive regulation of metanephric mesenchymal cell migration, and Regulation of forebrain neuron differentiation. Each is linked with KCNC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNC2-to-partner and partner-to-KCNC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway grouped by KCNC2-low versus KCNC2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC2→partner) and Y-score (partner→KCNC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway →	-0.538	-0.658	.009	.001	3	2
LUNG_SCLC	Positive regulation of metanephric mesenchymal cell migration →	-0.538	-0.658	.009	.001	3	2
LUNG_SCLC	Regulation of forebrain neuron differentiation →	-0.173	-0.830	<.001	.005	3	2
LUNG_SCLC	Positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway →	-0.538	-0.658	.009	.001	3	2
BLOOD_Leukemia	Interleukin-9-mediated signaling pathway →	+0.152	+0.049	.001	.004	3	2
BLOOD_Leukemia	Cellular response to interleukin-9 →	+0.152	+0.049	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway by KCNC2 expression — LUNG_SCLC

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