KCNC2

Across TCGA cell cohorts, KCNC2 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNC2-associated genes across cancer lineages are OR2L8, GJA8, and ALPI. Each is linked with KCNC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNC2-to-partner and partner-to-KCNC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L8 grouped by KCNC2-low versus KCNC2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC2→partner) and Y-score (partner→KCNC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2L8 →	+0.026	+4.169	<.001	.002	3	2
SKIN	GJA8 →	+0.014	+2.777	<.001	.004	3	1
SKIN	ALPI →	+0.006	+2.669	.002	.004	3	1
SKIN	PNOC →	+0.513	+4.041	.004	<.001	3	1
SKIN	TMEM95 →	+0.020	+2.977	<.001	.006	3	1
SKIN	OR2H2 →	+0.123	+3.259	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

OR2L8 by KCNC2 expression — BLOOD_Lymphoma

Explore this box plot interactively →