KCNB1

Across TCGA patient cohorts, KCNB1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,660 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNB1-associated genes across cancer lineages are BCAS1, SCML2, and FKTN. Each is linked with KCNB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNB1-to-partner and partner-to-KCNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNB1 versus BCAS1 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNB1→partner) and Y-score (partner→KCNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BCAS1 →	+2.510	+2.019	<.001	.001	3	2
LSCC	SCML2 →	-2.115	-1.597	<.001	<.001	3	1
LSCC	FKTN →	-0.683	-1.308	<.001	.007	3	1
LSCC	NEIL3 →	-0.981	-1.676	.005	.004	3	1
LSCC	NCAPG →	-1.019	-1.597	.002	<.001	3	1
LSCC	FBXO5 →	-0.728	-1.496	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,660 associations by consensus.

KCNB1 vs BCAS1 — LSCC

Explore this scatter interactively →