KCNAB3

Across TCGA patient cohorts, KCNAB3 mutation is significantly associated with the RNA expression of many other genes, with 2,224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNAB3-associated genes across cancer lineages are RNA5SP325, MIR8053, and CBX1P5. Each is linked with KCNAB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNAB3-to-partner and partner-to-KCNAB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP325 grouped by KCNAB3-low versus KCNAB3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNAB3→partner) and Y-score (partner→KCNAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP325 →	+0.289	+4.038	<.001	<.001	3	3
BRCA	MIR8053 →	+0.472	+5.409	<.001	.005	3	2
COAD	CBX1P5 →	+0.075	+4.602	<.001	.003	3	2
BLCA	RN7SL66P →	+0.190	+5.177	<.001	.007	3	2
UCEC	CENPM →	+0.643	+3.470	.002	.002	3	2
UCEC	POLE2 →	+0.670	+3.721	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,224 associations by consensus.

RNA5SP325 by KCNAB3 expression — SKCM

Explore this box plot interactively →