KCNAB2

Across TCGA patient cohorts, KCNAB2 mutation is significantly associated with the RNA expression of many other genes, with 2,122 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNAB2-associated genes across cancer lineages are MIR5707, RNU6-644P, and RNU6-445P. Each is linked with KCNAB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNAB2-to-partner and partner-to-KCNAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5707 grouped by KCNAB2-low versus KCNAB2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNAB2→partner) and Y-score (partner→KCNAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR5707 →	+0.707	+4.870	.002	.002	3	3
CESC	RNU6-644P →	+0.361	+4.193	.002	.009	3	2
BRCA	RNU6-445P →	+0.247	+7.731	<.001	.009	3	2
UCEC	MIR6803 →	+0.172	+4.671	<.001	.002	3	2
UCEC	MIR7974 →	+0.662	+2.756	<.001	<.001	3	2
LIHC	TRGJP1 →	+0.503	+5.108	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,122 associations by consensus.

MIR5707 by KCNAB2 expression — COAD

Explore this box plot interactively →