KCNAB2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNAB2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNAB2-associated genes across cancer lineages are PTH. Each is linked with KCNAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNAB2-to-partner and partner-to-KCNAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by KCNAB2-low versus KCNAB2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNAB2→partner) and Y-score (partner→KCNAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPTH →+0.049+3.684<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PTH by KCNAB2 expression — LARGE_INTESTINE

Box plot of PTH in KCNAB2-low vs KCNAB2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration