KCNAB1

Across TCGA cell cohorts, KCNAB1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNAB1-associated genes across cancer lineages are C1orf68, PRORY, and OR51J1. Each is linked with KCNAB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNAB1-to-partner and partner-to-KCNAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf68 grouped by KCNAB1-low versus KCNAB1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNAB1→partner) and Y-score (partner→KCNAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	C1orf68 →	+0.011	+3.681	<.001	.009	3	1
SKIN	PRORY →	+0.573	+4.688	.002	<.001	3	1
SKIN	OR51J1 →	+0.080	+4.347	<.001	.001	3	1
BLOOD_Leukemia	DPT →	+1.493	+3.769	<.001	.008	3	1
BLOOD_Leukemia	TMEM196 →	+0.036	+3.874	<.001	.005	3	1
BLOOD_Leukemia	GSG1L2 →	+0.034	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

C1orf68 by KCNAB1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →