KCNAB1-AS1

Across TCGA pan-cancer cohorts, KCNAB1-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated KCNAB1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher KCNAB1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNAB1-AS1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

UCS, KICH, and ESCA are the cancer types where KCNAB1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.170	0.697	<.001	108	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
ESCA	OS	Tertile	IV	0.135	0.568	.031	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
BRCA	OS	Tertile	III,IV	0.724	0.855	.012	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
BLCA	OS	Tertile	All	0.346	0.696	.022	18	view →
COAD	OS	Tertile	II,III,IV	0.233	0.788	.031	18	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
THYM	DFS	Tertile	All	0.092	0.871	<.001	9	view →
LGG	OS	Tertile	All	0.791	0.902	.008	9	view →
MESO	OS	Tertile	III,IV	0.213	0.585	.040	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

KCNAB1-AS1–UCS (OS)

Open the UCS breakdown →