KCNA7

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNA7 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNA7-associated genes across cancer lineages are 123138, WYE-125132, and PF-00299804. Each is linked with KCNA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA7-to-partner and partner-to-KCNA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123138 grouped by KCNA7-low versus KCNA7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA7→partner) and Y-score (partner→KCNA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINE123138 →+0.333+2.649.024.04631
LARGE_INTESTINEWYE-125132 →+0.516+2.652.044.04531
LARGE_INTESTINEPF-00299804 →+0.536+2.652.022.04531
LARGE_INTESTINETorin 2 →+0.537+2.655.047.04431
LARGE_INTESTINEAST-1306 →+0.457+2.652.042.04531
LARGE_INTESTINECD532 →+0.461+2.652.021.04531
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

123138 by KCNA7 expression — LARGE_INTESTINE

Box plot of 123138 in KCNA7-low vs KCNA7-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration