KCNA6

Across TCGA cell cohorts, KCNA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,642 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNA6-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Intermembrane lipid transfer, and CAMP/PKA signal transduction. Each is linked with KCNA6 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNA6-to-partner and partner-to-KCNA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by KCNA6-low versus KCNA6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA6→partner) and Y-score (partner→KCNA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of double-strand break repair via homologous recombination →	+0.069	+0.555	<.001	<.001	3	4
BLOOD_Lymphoma	Intermembrane lipid transfer →	+0.058	+0.549	<.001	<.001	3	4
BLOOD_Leukemia	CAMP/PKA signal transduction →	+0.120	+1.206	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of amyloid precursor protein catabolic process →	-0.091	-0.601	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of telomere capping →	+0.058	+0.632	<.001	<.001	3	4
BLOOD_Lymphoma	Regulation of integrin-mediated signaling pathway →	-0.168	-0.570	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,642 associations by consensus.

Regulation of double-strand break repair via homologous recombination by KCNA6 expression — BLOOD_Lymphoma

Explore this box plot interactively →