KCNA5

Across TCGA cell cohorts, KCNA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNA5-associated GO terms across cancer lineages are Peptide hormone processing, Negative regulation of interleukin-8 production, and Positive regulation of Wnt signaling pathway, planar cell polarity pathway. Each is linked with KCNA5 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNA5-to-partner and partner-to-KCNA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptide hormone processing grouped by KCNA5-low versus KCNA5-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA5→partner) and Y-score (partner→KCNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Peptide hormone processing →	-0.121	-0.347	<.001	.005	3	4
BLOOD_Leukemia	Negative regulation of interleukin-8 production →	-0.060	-0.478	.005	.007	3	4
BLOOD_Leukemia	Positive regulation of Wnt signaling pathway, planar cell polarity pathway →	-0.820	-0.696	<.001	.007	3	3
BLOOD_Leukemia	Regulation of neurotrophin production →	+0.796	+0.770	<.001	.003	3	3
SKIN	AMPA selective glutamate receptor signaling pathway →	-0.566	-0.011	.009	.005	3	2
BLOOD_Leukemia	Regulation of intracellular transport of viral material →	+0.112	+0.484	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Peptide hormone processing by KCNA5 expression — BLOOD_Leukemia

Explore this box plot interactively →