KCNA4

Across TCGA patient cohorts, KCNA4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,009 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNA4-associated genes across cancer lineages are PRODH, RASL10A, and NEFH. Each is linked with KCNA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA4-to-partner and partner-to-KCNA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNA4 versus PRODH in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA4→partner) and Y-score (partner→KCNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.823	+0.621	.001	<.001	3	1
GBM	RASL10A →	+0.932	+0.781	<.001	<.001	3	1
GBM	NEFH →	+1.155	+0.676	<.001	<.001	3	1
GBM	CBX7 →	+0.608	+0.737	<.001	<.001	3	1
GBM	ACR →	+0.093	+0.431	.002	.006	3	1
GBM	SYNGR1 →	+0.687	+0.659	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,009 associations by consensus.

KCNA4 vs PRODH — GBM

Explore this scatter interactively →