KCNA2

Across TCGA patient cohorts, KCNA2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,081 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNA2-associated genes across cancer lineages are PRODH, MFNG, and PIK3IP1. Each is linked with KCNA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA2-to-partner and partner-to-KCNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNA2 versus PRODH in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA2→partner) and Y-score (partner→KCNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.879	+0.662	.001	.006	3	1
GBM	MFNG →	+0.444	+0.484	.008	.009	3	1
GBM	PIK3IP1 →	+0.499	+0.539	.001	<.001	3	1
GBM	SOX10 →	+1.600	+0.633	<.001	.001	3	1
GBM	SUN2 →	+0.526	+0.848	<.001	<.001	3	1
GBM	RASL10A →	+1.052	+0.687	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,081 associations by consensus.

KCNA2 vs PRODH — GBM

Explore this scatter interactively →