KCNA2

Across TCGA cell cohorts, KCNA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,718 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCNA2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Aerobic respiration, and Epigenetic regulation of gene expression. Each is linked with KCNA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCNA2-to-partner and partner-to-KCNA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by KCNA2-low versus KCNA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA2→partner) and Y-score (partner→KCNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.069	+2.179	<.001	<.001	3	7
BONE	Aerobic respiration →	+0.068	+1.895	<.001	.001	3	6
BONE	Epigenetic regulation of gene expression →	+0.064	+2.317	<.001	<.001	3	6
BONE	Regulation of RNA splicing →	+0.070	+2.100	.002	.005	3	6
BONE	Cardiac muscle contraction →	-0.067	-2.061	<.001	.002	3	6
BONE	Detection of external stimulus →	-0.084	-2.427	.006	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,718 associations by consensus.

Positive regulation of DNA repair by KCNA2 expression — BONE

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