KCNA1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,546 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNA1-associated proteins across cancer lineages are SEPTIN7, NUMBL, and TLN2. Each is linked with KCNA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNA1-to-partner and partner-to-KCNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNA1 versus SEPTIN7 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA1→partner) and Y-score (partner→KCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSEPTIN7 →+0.353+1.189<.001<.00135
BRCANUMBL →+0.397+0.247<.001<.00135
HNSCTLN2 →+0.615+0.443<.001<.00135
BRCAPRICKLE2_S806 →+0.659+0.247<.001<.00134
HNSCARL3 →+0.335+0.567.001<.00134
COADRCN3 →+0.666+0.127<.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,546 associations by consensus.

KCNA1 vs SEPTIN7 — GBM

Per-sample scatter of KCNA1 vs SEPTIN7 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration