KCNA1

Across TCGA patient cohorts, KCNA1 mutation is significantly associated with the total protein of many other genes, with 79 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNA1-associated genes across cancer lineages are FASN, eIF4E, and ASNS. Each is linked with KCNA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNA1-to-partner and partner-to-KCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by KCNA1-low versus KCNA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA1→partner) and Y-score (partner→KCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.208	+1.180	.042	.005	3	5
STAD	eIF4E →	+0.317	+3.021	<.001	.017	3	4
COAD	ASNS →	+0.650	+2.906	<.001	.001	3	4
STAD	ACC1 →	+0.540	+3.000	.012	.034	3	3
COAD	Bad_pS112 →	-0.144	-1.654	.021	.011	3	3
COAD	Caspase-7-cleavedD198 →	+0.999	+3.000	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

FASN by KCNA1 expression — UCEC

Explore this box plot interactively →