KCNA1

Across TCGA cell cohorts, KCNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 624 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KCNA1-associated GO terms across cancer lineages are mRNA export from nucleus, Regulation of transcription by RNA polymerase I, and Regulation of stem cell population maintenance. Each is linked with KCNA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNA1-to-partner and partner-to-KCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by KCNA1-low versus KCNA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA1→partner) and Y-score (partner→KCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	mRNA export from nucleus →	+0.071	+0.009	<.001	.001	2	4
LARGE_INTESTINE	Regulation of transcription by RNA polymerase I →	+0.066	+0.005	.001	.007	3	3
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.072	+2.492	.002	<.001	3	3
LUNG_SCLC	Positive regulation of cell proliferation involved in heart morphogenesis →	+0.140	+2.103	.001	.009	3	3
LUNG_SCLC	Positive regulation of lipid transport →	-0.075	-2.547	.004	.001	3	3
LUNG_SCLC	Regulation of cell adhesion involved in heart morphogenesis →	+0.211	+2.334	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 624 associations by consensus.

mRNA export from nucleus by KCNA1 expression — OVARY

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