KCNA1

Across TCGA cell cohorts, KCNA1 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNA1-associated genes across cancer lineages are ASZ1, MYH6, and GALNTL5. Each is linked with KCNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA1-to-partner and partner-to-KCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by KCNA1-low versus KCNA1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA1→partner) and Y-score (partner→KCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ASZ1 →	+0.403	+4.050	<.001	.001	3	2
LUNG_NSCLC_LUAD	MYH6 →	+0.141	+3.082	<.001	.005	3	2
LUNG_NSCLC_LUAD	GALNTL5 →	+0.043	+3.374	<.001	.002	3	1
LUNG_NSCLC_LUAD	CSH1 →	+0.035	+3.665	.001	<.001	3	1
LUNG_NSCLC_LUAD	FBXO40 →	+0.006	+3.189	<.001	.007	3	1
LUNG_NSCLC_LUAD	PROP1 →	+0.017	+3.564	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

ASZ1 by KCNA1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →