KCMF1

Across TCGA pan-cancer cohorts, KCMF1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated KCMF1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KCMF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KCMF1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where KCMF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.615	1.000	.001	19	view →
HNSC	DFS	Median	II,III,IV	0.792	0.553	.006	17	view →
LUAD	DFS	Median	All	0.530	0.779	.017	16	view →
OV	DFS	Median	All	0.569	0.938	.009	8	view →
UCEC	DFS	Quartile	II,III,IV	1.000	0.465	.025	4	view →
PDAC	OS	Median	IV	0.836	0.491	.024	3	view →
LSCC	OS	Tertile	All	0.797	0.903	.021	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

KCMF1–CCRCC (OS)

Open the CCRCC breakdown →