KBTBD7

Across TCGA patient cohorts, KBTBD7 mutation is significantly associated with the RNA expression of many other genes, with 3,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD7-associated genes across cancer lineages are SKA1, C5orf22, and XAGE1B. Each is linked with KBTBD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both KBTBD7-to-partner and partner-to-KBTBD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by KBTBD7-low versus KBTBD7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD7→partner) and Y-score (partner→KBTBD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.617	+2.523	<.001	<.001	3	3
UCEC	C5orf22 →	+0.430	+2.191	.002	.001	3	3
BLCA	XAGE1B →	+0.121	+2.773	.001	.008	3	3
UCEC	PRC1 →	+0.589	+2.008	<.001	<.001	3	3
UCEC	ZNF611 →	+0.348	+1.377	.005	.009	3	3
UCEC	CD207 →	-0.719	-3.311	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,046 associations by consensus.

SKA1 by KBTBD7 expression — UCEC

Explore this box plot interactively →