KBTBD7

Across TCGA cell cohorts, KBTBD7 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KBTBD7-associated genes across cancer lineages are LY86, KRT85, and OOSP2. Each is linked with KBTBD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD7-to-partner and partner-to-KBTBD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY86 grouped by KBTBD7-low versus KBTBD7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD7→partner) and Y-score (partner→KBTBD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LY86 →	+0.058	+3.464	<.001	.004	3	1
LARGE_INTESTINE	KRT85 →	+0.385	+3.408	<.001	<.001	3	1
LARGE_INTESTINE	OOSP2 →	+0.007	+3.240	<.001	.004	3	1
LARGE_INTESTINE	FAM170A →	+0.079	+3.555	.001	.003	3	1
LARGE_INTESTINE	ZNF804B →	+0.013	+3.678	<.001	.001	3	1
LARGE_INTESTINE	PRORY →	+0.420	+3.639	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

LY86 by KBTBD7 expression — LARGE_INTESTINE

Explore this box plot interactively →