KBTBD6

Across TCGA patient cohorts, KBTBD6 mutation is significantly associated with the RNA expression of many other genes, with 2,895 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD6-associated genes across cancer lineages are RNU6-927P, NOCT, and AP1S3. Each is linked with KBTBD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both KBTBD6-to-partner and partner-to-KBTBD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-927P grouped by KBTBD6-low versus KBTBD6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD6→partner) and Y-score (partner→KBTBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-927P →	+0.151	+4.897	<.001	.002	3	3
UCEC	NOCT →	+0.525	+2.671	<.001	<.001	3	2
UCEC	AP1S3 →	+0.522	+2.502	<.001	.001	3	2
UCEC	C18orf25 →	+0.345	+2.338	.007	.003	3	2
UCEC	CCSAP →	+0.470	+1.737	.006	.002	3	2
UCEC	GBP5 →	+1.269	+3.180	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,895 associations by consensus.

RNU6-927P by KBTBD6 expression — SKCM

Explore this box plot interactively →