KBTBD6

Across TCGA cell cohorts, KBTBD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,935 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KBTBD6-associated GO terms across cancer lineages are Sister chromatid biorientation, Ornithine transport, and Ribosomal protein import into nucleus. Each is linked with KBTBD6 in more than 14 cancer types. Because this analysis shows association rather than direction, both KBTBD6-to-partner and partner-to-KBTBD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid biorientation grouped by KBTBD6-low versus KBTBD6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD6→partner) and Y-score (partner→KBTBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Sister chromatid biorientation →	+0.158	+0.725	.006	.005	3	15
PANCREAS	Ornithine transport →	+0.174	+0.903	<.001	<.001	3	14
CNS	Ribosomal protein import into nucleus →	+0.095	+0.746	<.001	<.001	3	14
SOFT_TISSUE	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.099	+0.767	<.001	<.001	3	14
BLOOD_Leukemia	Mitochondrial L-ornithine transmembrane transport →	+0.258	+0.833	.004	<.001	3	13
STOMACH	Regulation of antigen processing and presentation →	-0.176	-0.839	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,935 associations by consensus.

Sister chromatid biorientation by KBTBD6 expression — LUNG_SCLC

Explore this box plot interactively →