KBTBD6

Across TCGA cell cohorts, KBTBD6 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KBTBD6-associated genes across cancer lineages are TAS2R7, CSN2, and CPLX4. Each is linked with KBTBD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD6-to-partner and partner-to-KBTBD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R7 grouped by KBTBD6-low versus KBTBD6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD6→partner) and Y-score (partner→KBTBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAS2R7 →	+0.014	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CSN2 →	+0.031	+3.684	<.001	.006	3	1
LARGE_INTESTINE	CPLX4 →	+0.027	+4.392	.001	.004	3	1
LARGE_INTESTINE	LCE1D →	+0.334	+4.217	<.001	.001	3	1
LARGE_INTESTINE	KRTAP21-2 →	+0.072	+3.930	<.001	.003	3	1
LARGE_INTESTINE	OR2J1 →	+0.004	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

TAS2R7 by KBTBD6 expression — LARGE_INTESTINE

Explore this box plot interactively →