KBTBD3

Across TCGA cell cohorts, KBTBD3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KBTBD3-associated genes across cancer lineages are FHL5, KIR2DL1, and PRSS45P. Each is linked with KBTBD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD3-to-partner and partner-to-KBTBD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FHL5 grouped by KBTBD3-low versus KBTBD3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD3→partner) and Y-score (partner→KBTBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FHL5 →	+0.008	+4.044	.008	.003	3	1
CNS	KIR2DL1 →	+0.111	+4.201	<.001	.003	3	1
CNS	PRSS45P →	+0.062	+4.201	<.001	.003	3	1
CNS	KIR2DS4 →	+0.030	+3.643	<.001	.007	3	1
LARGE_INTESTINE	OR2T8 →	+0.155	+3.584	.001	.004	3	1
LARGE_INTESTINE	C16orf96 →	+0.519	+3.520	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

FHL5 by KBTBD3 expression — CNS

Explore this box plot interactively →