KBTBD13

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KBTBD13 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KBTBD13 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher KBTBD13 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KBTBD13 expression acts as an unfavorable survival marker.

SCLC and LUSC are the cancer types where KBTBD13 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SCLCDFSMedianAll0.1920.793.0176view →
LUSCDFSMedianII,III,IV0.1990.748.0066view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

KBTBD13–SCLC (DFS)

Kaplan–Meier survival curve for KBTBD13 mutant vs wild-type samples in SCLC.

Open the SCLC breakdown →

Exploration