KBTBD12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KBTBD12 mutation is significantly associated with the RNA expression of many other genes, with 3,489 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD12-associated genes across cancer lineages are DCLRE1C, TYW3, and ABLIM2. Each is linked with KBTBD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD12-to-partner and partner-to-KBTBD12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD12→partner) and Y-score (partner→KBTBD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDCLRE1C →+0.337+2.949.005<.00132
UCECTYW3 →+0.468+3.850<.001<.00132
UCECABLIM2 →-0.477-2.459.003<.00132
UCECSTK17A →+0.537+2.949<.001<.00132
UCECC9orf64 →+0.713+2.186<.001.00132
UCECZNF367 →+0.733+2.070<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,489 associations by consensus.

Exploration