KBTBD11

Across TCGA patient cohorts, KBTBD11 mutation is significantly associated with the RNA expression of many other genes, with 3,981 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD11-associated genes across cancer lineages are MIR4510, PTPN11, and TIGD2. Each is linked with KBTBD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD11-to-partner and partner-to-KBTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by KBTBD11-low versus KBTBD11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD11→partner) and Y-score (partner→KBTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.236	+4.757	<.001	.004	3	2
UCEC	PTPN11 →	+0.534	+2.961	.001	<.001	3	2
UCEC	TIGD2 →	+0.575	+1.981	<.001	<.001	3	2
UCEC	LRRC57 →	+0.430	+2.263	<.001	<.001	3	2
UCEC	C5orf24 →	+0.515	+1.938	.001	.001	3	2
UCEC	TRAPPC6B →	+0.422	+1.949	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,981 associations by consensus.

MIR4510 by KBTBD11 expression — CESC

Explore this box plot interactively →