KBTBD11

Across TCGA patient cohorts, KBTBD11 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD11-associated genes across cancer lineages are ATM, EGFR_pY1068, and N-Cadherin. Each is linked with KBTBD11 in more than 2 cancer types. Because this analysis shows association rather than direction, both KBTBD11-to-partner and partner-to-KBTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KBTBD11-low versus KBTBD11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD11→partner) and Y-score (partner→KBTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.490	-3.571	.003	.002	3	3
UCEC	EGFR_pY1068 →	-0.253	-1.874	.005	.049	3	2
UCEC	N-Cadherin →	+0.220	+1.502	.004	.030	3	2
UCEC	PDCD4 →	-0.517	-1.847	.002	.008	3	2
UCEC	STAT3_pY705 →	-0.323	-1.847	<.001	.008	3	2
UCEC	Stathmin →	+0.113	+1.502	.025	.030	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

ATM by KBTBD11 expression — UCEC

Explore this box plot interactively →