KBTBD11

Across TCGA cell cohorts, KBTBD11 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KBTBD11-associated genes across cancer lineages are IL9, FAM163B, and ASB17. Each is linked with KBTBD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD11-to-partner and partner-to-KBTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL9 grouped by KBTBD11-low versus KBTBD11-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD11→partner) and Y-score (partner→KBTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IL9 →	+0.130	+5.087	<.001	.004	3	1
URINARY_TRACT	FAM163B →	+0.076	+5.087	<.001	.004	3	1
STOMACH	ASB17 →	+0.035	+4.432	<.001	.003	3	1
BLOOD_Lymphoma	PPY →	+0.564	+3.736	<.001	.009	3	1
BLOOD_Lymphoma	GRXCR1 →	+0.017	+4.058	<.001	.009	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.050	+2.994	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

IL9 by KBTBD11 expression — URINARY_TRACT

Explore this box plot interactively →