Across TCGA pan-cancer cohorts, KAZN Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KAZN data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KAZN Mutation is associated with better overall survival. In most high-consensus cancer types, elevated KAZN expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, CESC, and SARC are the cancer types where KAZN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.863	.014	18	view →
CESC	DFS	Median	All	0.248	0.746	.001	12	view →
SARC	OS	Median	All	0.127	0.860	<.001	6	view →
LUAD	OS	Median	II,III,IV	0.090	0.677	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: KAZN tumor-vs-normal RNA expression · all KAZN data types